Formulation of the Polymeric Double Networks (DNs) for Biomedical Applications with Physicochemical Properties to Resemble a Biological Tissue

Single-network hydrogels can have an internal porous structure and biocompatibility, but lower mechanical properties. Combining these properties with another biocompatible mechanically strong network help in mimicking the extracellular matrix of native tissues to make them suitable for tissue scaffolds desired performance. In current objective, we combine poly (ethylene glycol) dimethacrylate (PEGDMA) macromer polysaccharides as two components double networks (DN) synergistic effects both resulting interpenetrating polymeric making it functional replacement injured tissues. The were characterized by physical like swelling ratio, tensile compressive modulus, rheological behavior. chemical composition was studied using Fourier transform infrared spectroscopy (FTIR), thermal behavior differential scanning calorimetry (DSC) experiments. Biodegradability strength are gained (DN), thus resemble more living DN tested cell compatibility possible application engineering. Furthermore, may allow their tissue-engineered scaffolds.